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The Zhang Lab 

Welcome to the Zhang Lab. We are a plant biotechnology lab in the department of Biology at James Madison University. 

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Our Research 

The ever-growing global population and changing climate necessitate the development of resilient crops to secure higher yield and better quality through enhanced tolerance to biotic and abiotic stresses. To achieve this goal, our research aims to deepen the understanding of the molecular and biochemical basis of plant defense against plant bacterial pathogens as well as develop and apply advanced genome editing technologies for gene discovery and plant trait improvement, with the ultimate goal of engineering economically important crops and vegetables for disease resistance. 

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Latest Publications

Helper NLRs Nrc2 and Nrc3 act codependently with Prf/Pto and activate MAPK signaling to induce immunity in tomato
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The two helper NLRs, Nrc2 and Nrc3, act codependently with the Prf/Pto complex and induce the downstream MAPK signaling leading to programed cell death (PCD), a key feature of effector-triggered immune responses. This results in disease resistance against the bacterial pathogen Pseudomonas Syringae pv. tomato (Pst) in tomato.

- The Plant Journal 117 (1): 7-22

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